What may be the most important message of all is that e-cigarettes and vaping come with many health unknowns. Dr. Patrick O’Connor, Yale Medicine’s Chief of General Internal Medicine, adds, “You see plumes of what looks like steam coming out of people’s mouths on the street when they are vaping, and I think they assume it’s mostly safe, mostly water. But these liquids used in vaping are filled with all kinds of stuff [like nicotine, marijuana, flavoring agents, chemicals], and we don’t always know what else is in there,” he says.

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